Debate about a wide scope of political issues at the federal or state level, domestic and international US policy.Impact of those policies in our quality of live.
 
HomePortalGalleryFAQSearchRegisterLog in
ENROLL AS A MEMBER TO ENJOY QUICK ACCESS TO HARD TO FIND INFO. BE THE MOST INFORMED! ENROLL TODAY, WE WANT TO HEAR YOUR VOICE!
Search
 
 

Display results as :
 
Rechercher Advanced Search
Navigation
 Portal
 Index
 Memberlist
 Profile
 FAQ
 Search
Affiliates
free forum
 


Poll
Do you think the 911 events were an inside job , with full involment of Bush cabinet over the attack to our own people?
I believe was an inside job, the evidence is out there.
81%
 81% [ 25 ]
I don't believe in conspiracy theories, but I understand some government agencies were trying to hide theirs errors.
3%
 3% [ 1 ]
Whoever believe in the Inside job theory is out of his mind.
13%
 13% [ 4 ]
I'm not informed enough to made an educated choice.
3%
 3% [ 1 ]
Total Votes : 31
Who is online?
In total there is 1 user online :: 0 Registered, 0 Hidden and 1 Guest

None

Most users ever online was 53 on Thu Dec 19, 2013 10:48 pm
Place your ad here

Share | 
 

 New Vaccination Strategy May Protect Against Both Lethal 1918 And H5N1 Influenza Viruses

View previous topic View next topic Go down 
AuthorMessage
Admin
Admin
avatar

Posts : 127
Join date : 2009-08-18
Location : Tampa,Fl

PostSubject: New Vaccination Strategy May Protect Against Both Lethal 1918 And H5N1 Influenza Viruses   Mon Oct 05, 2009 4:32 am

ScienceDaily (June 20, 2009) — A new study suggests that vaccination with 1918 H1N1 influenza virus-like particles not only protected mice and ferrets against the lethal 1918 influenza virus, but also displayed cross-reactive immunity against the potentially pandemic H5N1 influenza virus.The researchers from the National Center for Immunization and Respiratory Diseases, Collaborating Centers for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; and Novavax, Inc., Rockville, Maryland report their findings in the June 2009 issue of the Journal of Virology.

More than 220,000 hospitalizations and approximately 36,000 deaths are attributed to influenza A viruses each year. Since the first confirmed human cases of avian influenza in 1997, more than 400 additional human H5N1 infections have occurred of which an estimated 60% have been fatal. As new subtypes continue to emerge and the threat of a pandemic is at its highest in decades, researchers are pursuing vaccine strategies that can induce cross-reactive immunity against multiple strains of influenza viruses.

In prior research virus-like particle (VLP) vaccines have proven to be a promising new technology at preventing diseases in humans. VLPs resemble their live-virus counterparts and are readily processed by the immune system, however, they lack the RNA required for virus replication.

In this study researchers generated VLPs from the structural proteins of the 1918 H1N1 virus and compared their ability to protect mice and ferrets against a reconstructed 1918 virus and the highly pathogenic avian H5N1 virus that was isolated from a fatal human case. When immunized twice intranasally with H1N1 VLPs mice were highly protected against a lethal challenge with both the 1918 and H5N1 virus. In contrast, mice receiving two intramuscular immunizations of 1918 VLPs were only protected against the 1918 viral challenge. Mucosal vaccination with 1918 VLPs induced higher levels of cross-reactivity in mice and complete survival in ferrets challenged with a lethal dose of the H5N1 virus. Only a 50% survival rate was noted in intramuscularly immunized animals.

"These results suggest a strategy of VLP vaccination against a pandemic virus and one that stimulates heterotypic immunity against an influenza virus strain with threatening pandemic potential," say the researchers.

Journal reference:
Perrone et al. Intranasal Vaccination with 1918 Influenza Virus-Like Particles Protects Mice and Ferrets from Lethal 1918 and H5N1 Influenza Virus Challenge. Journal of Virology, 2009; 83 (11): 5726 DOI: 10.1128/JVI.00207-09
Adapted from materials provided by American Society for Microbiology, via EurekAlert!, a service of AAAS.

_________________
"The men the American people admire most extravagantly are the greatest liars; the men they detest most violently are those who try to tell them the truth."
"All truth passes through three stages. First, it is ridiculed. Second, it is violently opposed. Third, it is accepted as being self-evident."
Arthur Schopenhauer
Back to top Go down
http://capitolhillbriefing.forumotion.com
 
New Vaccination Strategy May Protect Against Both Lethal 1918 And H5N1 Influenza Viruses
View previous topic View next topic Back to top 
Page 1 of 1
 Similar topics
-
» Buy and Hold Stock Strategy
» Softlogic explains pricing strategy, growth plans
» Buy and Hold Stock Strategy
» Whose strategy is the best to stay invested in the stock market.Pour your thoughts
» Understanding GARP Stock Investing Strategy

Permissions in this forum:You cannot reply to topics in this forum
Capitol Hill Inquirer :: Health Care :: The Swine Flu Vaccine-
Jump to: